206010070976 Craniocerebral injury Diseases 0.000 abstract description 93.239000003937 drug carrier Substances 0.000 claims description 6.239000008194 pharmaceutical composition Substances 0.000 claims description 9.206010053643 Neurodegenerative disease Diseases 0.000 claims description 25.239000011780 sodium chloride Substances 0.000 claims description 58.GAQWKARFCURWKO-HNNXBMFYSA-N Chemical compound GAQWKARFCURWKO-HNNXBMFYSA-N 0.000 claims abstract description 4.230000001684 chronic Effects 0.000 claims abstract description 9.230000000324 neuroprotective Effects 0.000 title abstract description 50.150000001875 compounds Chemical class 0.000 title claims description 201.Assignors: PIEPER, ANDREW A Application granted granted Critical Publication of US9902713B2 publication Critical patent/US9902713B2/en Status Active legal-status Critical Current Anticipated expiration legal-status Critical Links Assignors: McKnight, Steven L, READY, JOSEPH M Assigned to UNIVERSITY OF IOWA RESEARCH FOUNDATION reassignment UNIVERSITY OF IOWA RESEARCH FOUNDATION ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) Filing date Publication date Priority to US201361902680P priority Critical Priority to US201361912625P priority Priority to US201462002961P priority Priority to US15/035,909 priority patent/US9902713B2/en Priority to PCT/US2014/065054 priority patent/WO2015070234A2/en Application filed by University of Iowa Research Foundation UIRF, University of Texas System filed Critical University of Iowa Research Foundation UIRF Publication of US20160272619A1 publication Critical patent/US20160272619A1/en Assigned to BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM reassignment BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Original Assignee University of Iowa Research Foundation UIRF University of Texas System Priority date (The priority date is an assumption and is not a legal conclusion. University of Iowa Research Foundation UIRF Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.) Pieper Current Assignee (The listed assignees may be inaccurate.
Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Active Application number US15/035,909 Other versions US20160272619A1
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Google Patents Neuroprotective compounds and use thereofÄownload PDF Info Publication number US9902713B2 US9902713B2 US15/035,909 US201415035909A US9902713B2 US 9902713 B2 US9902713 B2 US 9902713B2 US 201415035909 A US201415035909 A US 201415035909A US 9902713 B2 US9902713 B2 US 9902713B2 Authority US United States Prior art keywords carbazol injury dibromo blast mice Prior art date Legal status (The legal status is an assumption and is not a legal conclusion. Google Patents US9902713B2 - Neuroprotective compounds and use thereof US9902713B2 - Neuroprotective compounds and use thereof